Severe Allergic Reaction: Anaphylaxis

Severe Allergic Reaction: Anaphylaxis

Our immune system protects us from foreign substances or allergens by producing histamine. This reaction to an allergen is known as an allergic reaction that causes inflammation, sneezing, or coughing. Some allergic reactions are mild but some are severe and life-threatening. These life-threatening allergic reactions are termed anaphylaxis. Anaphylaxis reactions are rapid and cause damage within seconds or minutes of exposure to an allergen. Rarely the reaction may occur days after the encounter with the allergen. The reaction may occur in phases with a gap of around 12 hours known as a biphasic reaction.

The immune system releases a high amount of chemicals against allergens that cause the body to go into a state of shock as well as the blood pressure drops suddenly, airways narrow causing difficulty in breathing. The blood vessels may burst causing edema (swelling due to accumulation of fluid in the body).

These reactions are triggered due to food like milk, eggs, fish, crustacean shellfish, wheat, soy, peanuts, or tree nuts, venom from insect stings like bees, wasps, and ants, or medication like antibiotics. People with allergic skin conditions or asthma are at high risk of anaphylaxis.

Common signs of anaphylaxis are itchy or raised skin, red skin rash; swollen eyes, lips, hands, and feet; feeling lightheaded or faint; swelling of the mouth, throat, or tongue that can lead to breathing and swallowing difficulties; wheezing; abdominal pain; nausea and vomiting; sudden collapse or unconsciousness.

Ways by which Pharmacy can help during Anaphylaxis

An authorized pharmacist can be a significant part of your medical services group. Pharmacists work with patients, insurance agencies, and drug organizations consistently. They assume a vital part in further developing admittance to drugs and tracking down ways of bringing down costs.

Pharmacists have an abundance of information that can help patients past filling prescriptions. Their direction ought to not the slightest bit supplant the guidance of your primary care physician.

  • Instruction about correctly using the prescribed medication: Your pharmacist will provide details about the prescribed medication, including:

    • The dosage to use.

    • When to take the medication.

    • How the medication works.

    • Ways the medication will help you.

  • They would consult insurance for information on copays and generic medicine options: Your pharmacist might recommend choices to decrease the expense or copay. A portion of the choices might include:

    • Reliable generic medication

    • Rebates

    • Drug card

  • Tell you about products to help reduce exposure to environmental allergens: Develop an open line of correspondence with your pharmacist. Pharmacists can likewise make sense of how to utilize these items intended to control allergens. They can propose practical strides to decrease triggers in your home. Some trigger decrease items include:

    • Dust mite-proof mattress and pillow covers

    • Dehumidifiers

    • Non-toxic pest control

    • Air filters

  • Check at fixings in prescriptions to decide whether they contain a known allergen: A few drugs might contain food allergens. The pharmacist can check for an allergen in a medicine. It's ideal to caution the drug store ahead of time before you get your prescription.

  • Talk to your primary care physician and pharmacist regarding the bad response to a medicine or incidental effects are an issue: Tell your PCP and pharmacist straightaway on the off chance that you have a hypersensitive response or terrible incidental effects to a drug. The specialist and pharmacist can cooperate to distinguish an adequate substitute.

The ways Pharmacist would Identify Anaphylaxis

Symptoms of anaphylaxis regularly start within 5 to 30 minutes of coming into contact with the allergen to which you are unfavorably susceptible. At times it might require over an hour for you to see anaphylactic symptoms.

Causes of Anaphylaxis

Symptoms that affect more than one part of the body and may include:

  • Red rash, with hives/welts, that are normally irritated (It is possible to have an extremely unfavorably susceptible response without skin symptoms.)

  • Enlarged throat or enlarged region of the body (It is possible to have an extremely unfavorably susceptible response without skin symptoms.)

  • Wheezing

  • Passing out

Treatment of Severe Allergic Reaction: Anaphylaxis

  • Chest tightness

  • Trouble breathing, cough

  • Hoarse voice

  • Trouble swallowing

  • Vomiting

  • Diarrhea

  • Stomach cramping

  • Pale or red color to the face and body

  • The feeling of impending doom

Ordinarily, symptoms start within five to 30 minutes of coming into contact with the allergen. For instance, you could get stung by a honey bee or eat something with peanuts. However, symptoms can at times begin over an hour after the fact.

Management and Treatment

Epinephrine (adrenaline) injection is given immediately to the patient to treat an anaphylactic reaction. A maximum of 2 doses help in controlling the reaction. Intramuscular or intravenous injection is the easiest way to administer epinephrine as it provides a rapid increase in the plasma and tissue concentrations in the body.

It is important to control the reaction as early as possible as this might be life-threatening to the patient. Blood tests are done to measure the amount of tryptase enzyme as well as tests to determine the reason for allergy (if not known to the patient).

Symptoms of Anaphylaxis

Apart from the allergic reaction, it is important to treat the damage caused by an anaphylactic reaction like cardiopulmonary resuscitation (CPR) is given if breathing stops or the heart stops beating. Oxygen is given in case of breathing difficulty or antihistamines and cortisone are given to reduce the inflammation. Beta-agonist also helps in relieving breathing difficulties.

Knowing the triggers is important to avoid anaphylactic reactions in the future. Precaution is better than cure in case of an anaphylactic reaction. To avoid food and medicine allergies it is important to get an allergy test done and avoid the food to which the body is allergic too. For insect stings, doctors provide a preventative treatment called venom immunotherapy (or venom allergy shots).

Pharmacist’s importance help in Anaphylaxis


Anaphylaxis is the point at which you have an extreme unfavorably susceptible response to an allergen, for example, a specific food or bug nibble. Anaphylactic shock can life-compromise. On the off chance that you notice anaphylaxis symptoms, infuse yourself with epinephrine immediately. Then call 911 or get to the trauma center. Brief anaphylaxis treatment can save your life. Try to convey your injector to any place you go. Attempt to stay away from triggers. Assuming you have sensitivity symptoms that are difficult to control or you went into anaphylactic shock, converse with your medical services supplier.

Treatment of Anaphylaxis

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If you or anyone you know is suffering from a severe allergic reaction, our expert providers at ASP Cares will take care of your health and help you recover.

Call us on (210)-417-4567 to book an appointment with our specialists.

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